Study reveals early dementia risk factors; knowledge empowers

A recent study published in JAMA Neurology by the University of Exeter and Maastricht University sheds light on factors contributing to early-onset dementia, occurring before age 65. Analyzing data from over 350,000 participants under 65 in the UK, researchers identified 15 key factors influencing its development, with some surprising findings.

Among the notable risk factors are social isolation, lower education and socioeconomic status, carrying two copies of the APOE gene, vitamin D deficiency, hearing impairment, alcohol use disorder, abstinence from alcohol, depression, high C-reactive protein levels, lower handgrip strength, orthostatic hypotension, stroke, diabetes, and heart disease.

While some factors like genetic predisposition and socioeconomic status are beyond control, many others are modifiable through lifestyle changes. This study offers valuable insights as it examines young-onset dementia risk factors comprehensively, unlike previous studies focusing on late-onset dementia.

To mitigate the risk of early-onset dementia, experts recommend adopting specific lifestyle measures. Physical exercise is paramount, as it enhances neurocognitive function, promotes neurogenesis, and vasculogenesis, besides improving mood. A Mediterranean-based diet rich in vitamins, omega-3 fatty acids, and antioxidants is also recommended for its neuroprotective benefits.

Additionally, engaging in cognitive, mood, and social stimulation can help maintain brain health. Cognitive stimulation involves activities like learning a new language or attending seminars. Mood stimulation includes stress-reducing practices such as mindfulness and yoga. Social stimulation emphasizes face-to-face interactions and meaningful connections with others, particularly vital in the post-pandemic era.

While these lifestyle habits address only a portion of dementia risk factors, they serve as a solid foundation for reducing the likelihood of early-onset dementia. By incorporating these practices into daily life, individuals can take proactive steps to safeguard their cognitive health and overall well-being.

In summary, understanding the modifiable risk factors for early-onset dementia empowers individuals to make informed decisions about their lifestyle choices. By prioritizing physical activity, healthy eating, and mental and social engagement, one can mitigate the risk and promote brain health for years to come.

Repurposed article originally published in Buzz Feed